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. Author manuscript; available in PMC: 2016 Jun 30.

Published in final edited form as: Curr Opin Investig Drugs. 2005 Aug;6(8):845–853.

Table 3.

MIC values of SPK-843 and amphotericin B against a range of yeast.

Isolate	SPK-843				Amphotericin B
Isolate	MIC range (µg/ml)	MIC₅₀ (µg/ml)	MIC₉₀ (µg/ml)	Mean MIC (µg/ml)	MIC range (µg/ml)	MIC₅₀ (µg/ml)	MIC₉₀ (µg/ml)	Mean MIC (µg/ml)
C albicans	0.009 to 0.15	0.075	0.150	0.054	0.075 to 0.30	0.150	0.150	0.124
C glabrata	0.019 to 0.075	0.038	0.075	0.042	0.150 to 0.60	0.300	0.300	0.264
C krusei	0.019 to 0.3	0.075	0.300	0.080	0.150 to 0.30	0.300	0.300	0.227
C tropicalis	0.019 to 0.075	0.038	0.075	0.042	0.038 to 0.30	0.150	0.300	0.150
C neoformans	0.019 to 0.075	0.038	0.075	0.035	0.038 to 0.30	0.150	0.300	0.150
S cerevisiae	0.002 to 0.019	0.009	0.019	0.009	0.018 to 0.15	0.075	0.075	0.065