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. Author manuscript; available in PMC: 2016 Jun 30.
Published in final edited form as: Chem Rev. 2007 Dec 21;108(1):264–287. doi: 10.1021/cr078199m

Scheme 1.

Scheme 1

Synthesis of Lamellarins D (35) and H (37)a

a Reagents and conditions: (i) LDA, THF, 79, 63%; (ii) BrCH2CO2Et; (iii) cat. HCl, MeOH; (iv) Et3N, CH2Cl2, 34% (3 steps); (v) H2, Pd(OH)2/C, EtOAC, 82%; (vi) BBr3, CH2Cl2, 68%. (Reprinted with permission from ref 31. Copyright 1997 Elsevier B.V.)