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. 2016 Jun 29;11:29. doi: 10.1186/s13020-016-0103-z

Table 4.

Effects of P. kesiya and melphalan on apoptosis induction in U937 and HepG2 cells

IC₅₀ ratio		% Apoptotic cells
IC₅₀ of P. kesiya	IC₅₀ of Melphalan	U937	HepG2
0	1	43.1 ± 16.3	53.0 ± 6.1
1	0	42.5 ± 4.8^b	39.7 ± 2.6^a
1	1	100^a	100^a
0.1	1	77.0 ± 1.9^a	66.7 ± 3.1^a
0.2	1	100^a	74.9 ± 12.3^a
0.5	1	100^a	92.8 ± 1.3^a
1.5	1	100^a	98.3 ± 3.0^a
2	1	100^a	100^a
1	0.05	38.6 ± 6.1^a	62.4 ± 3.2^a
1	0.1	48.4 ± 3.8^a	87.9 ± 3.3^a
1	0.2	61.3 ± 3.3^a	90.3 ± 6.0^a
1	0.5	100^a	100^a
1	1.5	100^a	100^a
1	2	100^a	100^a

One-way ANOVA of percentage apoptotic cells compared with single treatment by melphalan at 1 × IC₅₀ in cancer cells

^aSignificant difference (P < 0.001)

^bNon-significant difference (P ≥ 0.001)