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. 2016 Jun 29;13:12. doi: 10.1186/s12987-016-0034-1

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Box and Whisker diagrams demonstrating differences in the mean/median, 25/75 % percentile and minimum-maximum of the, aquaporin-4 (AQP4) and interleukin-6 (IL6) concentrations in the cerebrospinal fluid before and 3 months after surgery compared to controls (top row). The total quantity of both parameters AQP4 and IL6 (middle row) was calculated by multiplying by the ventricular volume (bottom graph). Significant differences are marked with asterisks (*P < 0.01; **P <0.001; ***P < 0.0001, n = 14, 14, 10 for preoperative, postoperative and control groups, respectively