Table 2.
Pre and post-operative concentrations for aquaporin 4 and interleukin 6 and CSF volumes for dogs with hydrocephalus
| Dog number | Routine CSF examination | Pre-operative values AQP4 (ng/mL), total AQP4 (ng), IL-6 (IU/mL) total IL-6 (IU), CSF volume (mL) | Postoperative values AQP4 (ng/mL), total AQP4 (ng), IL-6 (IU/mL), total IL-6 (IU), CSF volume (mL) |
|---|---|---|---|
| 1 |
Protein 252 mg/L RBC 0/μL Cells 3/μL |
AQP4 12.78 Total AQP4 quantity 301.5 IL-6 63 Total IL-6 quantity 1486.8 CSF volume 23.6 |
AQP4 10.81 Total AQP4 quantity 28.51 IL-6 30 Total IL-6 quantity 84 CSF volume 2.8 |
| 2 |
Protein 276 mg/L RBC 280/μL Cells 1/μL |
AQP4 10.77 Total AQP4 quantity 223.5 IL-6 87 Total IL-6 quantity 2260.8 CSF volume 26.4 |
AQP4 10.2 Total AQP4 quantity 27.99 IL6 36 Total IL-6 quantity 96.62 CSF volume 2.6 |
| 3 |
Protein 276 mg/L RBC 291/μL Cells 5/μL |
AQP4 17.47 Total AQP4 quantity 391.33 IL-6 22 Total IL-6 quantity 492.8 CSF volume 22.4 |
AQP4 14.23 Total AQP4 quantity 150 IL-6 15 Total IL-6 quantity 61.1 CSF volume 10.6 |
| 4 |
Protein 240 mg/L RBC 0/μL Cells 1/μL |
AQP4 15.29 Total AQP4 quantity 455.56 IL-6 28 Total IL-6 quantity 834.4 CSF volume 29.8 |
AQP 49.71 Total AQP4 quantity 45.62 IL-6 13 Total IL-6 quantity 634.5 CSF volume 4.7 |
| 5 |
Protein 240 mg/L RBC 0/μL Cells 5/μL |
AQP4 13.51 Total AQP4 quantity 278.3 IL-6 39 Total IL-6 quantity 803.4 CSF volume 20.6 |
AQP4 5.3 Total AQP4 quantity 34.45 IL-6 21 Total IL-6 quantity 136.5 CSF volume 6.5 |
| 6 |
Protein 208 mg/L RBC 0/μl Cells 1/μl |
AQP4 10.33 Total AQP4 quantity 133.3 IL-6 51 Total IL-6 quantity 658.41 CSF volume 12.91 |
AQP4 9.9 Total AQP4 quantity 63.67 IL-6 32 Total IL-6 quantity 205.76 CSF volume 6.43 |
| 7 | Blood contamination |
AQP4 17.96 Total AQP4 quantity 467.67 IL-6 87 Total IL-6 quantity 2265.48 CSF volume 26.04 |
AQP4 8.93 Total AQP4 quantity 21.43 IL-6 37 Total IL-6 quantity 88.8 CSF volume 2.4 |
| 8 |
Protein 246 mg/L RBC 15/μL Cells 5/μL |
AQP4 8.46 Total AQP4 quantity 211.54 IL-6 62 Total IL-6quantity 1078.8 CSF volume 17.4 |
AQP4 10.77 Total AQP4 quantity 3.95 IL-6 21 Total IL-6 quantity 13.4 CSF volume 1.64 |
| 9 | Blood contamination |
AQP4 12.16 Total AQP4 quantity 472.45 IL-6 65 Total IL-6 quantity 1709.5 CSF volume 26.3 |
AQP4 2.41 Total AQP4 quantity 58.03 IL-6 40 Total IL-6 quantity 260 CSF volume 6.5 |
| 10 |
Protein 300.9 mg/L RBC 18/μL Cells 7/μL |
AQP4 19.19 Total AQP4 quantity 675.31 IL-6 66 Total IL-6 quantity 2323.2 CSF volume 35.2 |
AQP4 9.67 Total AQP4 quantity 190.95 IL-6 69 Total IL-6 quantity 1362.75 CSF volume:19.7 |
| 11 |
Protein 374 mg/L RBC 1/μL Cells 1/μL |
AQP4 14.63 Total AQP4 quantity 168.85 IL-6 54 Total IL-6 quantity 623.16 CSF volume 11.54 |
AQP4 16.2 Total AQP4 quantity 58.31 IL-6 45 Total IL-6 quantity 162 CSF volume 3.6 |
| 12 |
Protein 204 mg/L RBC 0/μL Cells 4/μL |
AQP4 7.1 Total AQP4 quantity 130.14 IL-6 89 Total IL-6 quantity 1631 CSF volume 18.33 |
AQP4 4.5 Total AQP4 quantity 42.93 IL-6 46 Total IL-6 quantity 438.84 CSF volume 9.54 |
Pre-, and post-operative determination of the ventricular volume (CSF volume), aquaporin-4 (AQP4) and interleukin-6 (IL-6) of the study group of 12 dogs with hydrocephalus. AQP4 and IL-6 have been multiplied by the total CSF volume, to give the total quantity in the CSF. The underlined entries (dogs 8 and 11) are dogs in which no decrease of AQP4 and IL-6 concentration was found after surgery although the total quantities were decreased (CSF cerebrospinal fluid, RBC red blood cell count)