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. 2016 Jun 29;13:170. doi: 10.1186/s12974-016-0636-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Neopterin levels in CSF (a) and serum (b) in hip fracture patients stratified regarding acute (delirium) and chronic cognitive impairment (neither: n = 56, chronic cognitive impairment only = 10, delirium only = 24, both = 40) p = 0.05 for CSF and p = 0.01 for serum (Kruskal-Wallis tests). The horizontal lines represent the median. Three patients (one with ‘neither’ and two with ‘delirium only’) had CSF neopterin above the upper margin of this figure. The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) cutoff of 3.44 was used as an indicator of chronic cognitive impairment (missing in five patients)