Abstract
Cerebral blood flow (CBF) was measured before and after intravenous injection of the cerebral vasodilator nicergoline in 13 patients with cerebrovascular disease. CBF increased in seven. The possibility that the effect of the drug in the remainder may have been masked by a fall of CBF which occurs during sequential measurement of patients at rest is discussed.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arcari G., Dorigotti L., Fregnan G. B., Glässer A. H. Vasodilating and alpha-receptor blocking activity of a new ergoline derivative. Br J Pharmacol. 1968 Nov;34(3):700P–700P. [PMC free article] [PubMed] [Google Scholar]
- Benzi G., Manzo L., De Bernardi M., Ferrara A., Sanguinetti L., Arrigoni E., Berté F. Action of lysergide, ephedrine, and nimergoline on brain metabolizing activity. J Pharm Sci. 1971 Sep;60(9):1320–1324. doi: 10.1002/jps.2600600906. [DOI] [PubMed] [Google Scholar]
- Olesen J., Paulson O. B., Lassen N. A. Regional cerebral blood flow in man determined by the initial slope of the clearance of intra-arterially injected 133Xe. Stroke. 1971 Nov-Dec;2(6):519–540. doi: 10.1161/01.str.2.6.519. [DOI] [PubMed] [Google Scholar]
- Palmer N. I., Thomas D. J., MacGillivray B. B., Du Boulay G. H., Marshall J., Russell R. R., Symon L. Variations in mean cerebral blood flow under anesthesia at rest and during cortical activation. Stroke. 1977 Mar-Apr;8(2):269–271. doi: 10.1161/01.str.8.2.269. [DOI] [PubMed] [Google Scholar]
- Wilkinson I. M., Bull J. W., Duboulay G. H., Marshall J., Russell R. W., Symon L. Regional blood flow in the normal cerebral hemisphere. J Neurol Neurosurg Psychiatry. 1969 Oct;32(5):367–378. doi: 10.1136/jnnp.32.5.367. [DOI] [PMC free article] [PubMed] [Google Scholar]