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. 2016 Jun 30;13:172. doi: 10.1186/s12974-016-0638-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Effect of interferon (IFN)-α treatment on fear extinction. Mean ± standard error of percent freezing compared to that of the vehicle. Rats (n = 8/group) were treated with 100, 200, or 400 IU IFN-α for the habituation, conditioning, and extinction trials. Vehicle or IFN-α was administrated after the rats experienced the habituation and conditioning trials. *p < 0.05 in the comparison (Tukey’s test) between vehicle and 400 IU IFN-α group. ^# p < 0.05 in the comparison between vehicle and 200 IU IFN-α group