Table 1.
Characteristics of Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Participants in the National Heart, Lung, and Blood Institute HIV-Cardiovascular Disease Collaborative, by Age Group
| Characteristic | Age 6–29 y |
Age 30–49 y |
Age 50–75 y |
|||
|---|---|---|---|---|---|---|
| HIV Uninfected (n = 58) | HIV Infected (n = 221) | HIV Uninfected (n = 221) | HIV Infected (n = 738) | HIV Uninfected (n = 386) | HIV Infected (n = 730) | |
| Female sex, No. (%) | 24 (41) | 78 (35) | 138 (62) | 371 (50) | 84 (22) | 247 (34) |
| Black race, No. (%) | 42 (72) | 137 (62) | 108 (49) | 316 (43) | 114 (30) | 272 (37) |
| Hispanic ethnicity, No. (%) | 14 (24) | 42 (19) | 55 (25) | 208 (28) | 26 (7) | 99 (14) |
| Height, mean (SD), cm | 156 (17) | 167 (14) | 168 (10) | 168 (10) | 174 (10) | 172 (10) |
| Weight, mean (SD), kg | 59 (29) | 68 (20) | 89 (24) | 80 (20) | 85 (17) | 80 (17) |
| SBP, mean (SD), mm Hg | 105 (12) | 111 (12) | 122 (17) | 118 (15) | 129 (16) | 125 (16) |
| Total cholesterol, mean (SD), mg/dL | 165 (35) | 151 (33) | 184 (40) | 174 (37) | 187 (37) | 182 (41) |
| HDL, mean (SD), mg/dL | 57 (16) | 44 (15) | 56 (17) | 47 (16) | 55 (17) | 50 (17) |
| Current use of hypertension medication, No. (%) | 0 (0) | 1 (<1) | 50 (23) | 139 (19) | 141 (37) | 314 (43) |
| Current use of lipid-lowering medication, No. (%) | 0 (0) | 1 (<1) | 22 (10) | 87 (12) | 122 (32) | 268 (37) |
| Current smoker, No. (%) | 0 (0) | 44 (20) | 81 (37) | 270 (37) | 96 (25) | 202 (28) |
| HCV infection, No. (%) | 0 (0) | 1 (<1) | 17 (8) | 78 (11) | 43 (11) | 182 (25) |
| Current use of HAART, No. (%) | 107 (48) | 413 (56) | 573 (78) | |||
| Suppressed HIV RNA level, No. (%)a | 23 (10) | 377 (51) | 557 (76) | |||
| Current CD4+ T-cell count, mean (SD), cells/µL | 485 (364) | 499 (292) | 579 (292) | |||
| History of AIDS, No. (%) | 149 (67) | 227 (31) | 228 (31) | |||
| CCA-IMT, mean (SD), µm | 597 (70) | 607 (75) | 725 (96) | 709 (115) | 803 (133) | 801 (145) |
| BIF-IMT, mean (SD), µm | 654 (104) | 671 (83) | 825 (141) | 802 (143) | 928 (165) | 900 (161) |
Abbreviations: BIF-IMT, carotid artery bifurcation intima-media thickness; CCA-IMT, common carotid artery intima-media thickness; HAART, highly active antiretroviral therapy; HCV, hepatitis C virus; HDL, high-density lipoprotein; HIV, human immunodeficiency virus; SBP, systolic blood pressure; SD, standard deviation.
a Defined as <80 copies/mL.