Table 2.
Classification, predicted ancestral serotypes and cps mutations of invasive nontypeable Streptococcus pneumoniae in South Africa, 2003–2013 (N = 39)

Bold type represents serotypes included in PCV13
SLV single-locus variant, differs at one of the seven alleles. DLV Double-locus variant, differs at two of the seven alleles
None Novel ST and therefore no serotype/ST association exists
ND not done, isolates have no cps genes
N/A Not applicable, resembles nontypeable pneumococci from carriage (no cps genes, but instead have typical nontypeable genes)
NP not predicted. Isolates have no cps genes and/or are associated with more than 1 serotype
aAs per Streptococcus pneumoniae multilocus sequence typing database (http://pubmlst.org/spneumoniae/, accessed March 2015)
bOther serotype/s associated with that ST. See comments
c glf pseudo gene present within the cps locus