Table 1.

Pathogen–antimicrobial combinations on which GLASS will gather data (Adapted by the Manual for Early Implementation, GLASS).

Pathogen	Antibacterial class	Antibacterial agents that may be used for ASTa,b
Escherichia coli	Sulfonamides and trimethoprim	Co-trimoxazole
	Fluoroquinolones	Ciprofloxacin or levofloxacin
	Third-generation cephalosporins	Ceftriaxone or cefotaxime and ceftazidime
	Fourth-generation cephalosporins	Cefepime
	Carbapenemsc	Imipenem, meropenem, ertapenem or doripenem
	Polymyxins	Colistin
	Penicillins	Ampicillin
Klebsiella pneumoniae	Sulfonamides and trimethoprim	Co-trimoxazole
	Fluoroquinolones	Ciprofloxacin or levofloxacin
	Third-generation cephalosporins	Ceftriaxone or cefotaxime and ceftazidime
	Fourth-generation cephalosporins	Cefepime
	Carbapenemsc	Imipenem, meropenem, ertapenem or doripenem
	Polymyxins	Colistin
Acinetobacter baumannii	Tetracyclines	Tigecycline or minocycline
	Aminoglycosides	Gentamicin and amikacin
	Carbapenemsc	Imipenem, meropenem, ertapenem or doripenem
	Polymyxins	Colistin
Staphylococcus aureus	Penicillinase-stable beta-lactams	Cefoxitind
Streptococcus pneumoniae	Penicillins	Oxacilline
		Penicillin G
	Sulfonamides and trimethoprim	Co-trimoxazole
	Third-generation cephalosporins	Ceftriaxone or cefotaxime
Salmonella spp.	Fluoroquinolones	Ciprofloxacin or levofloxacin
	Third-generation cephalosporins	Ceftriaxone or cefotaxime and ceftazidime
	Carbapenemsc	Imipenem, meropenem, ertapenem or doripenem
Shigella spp.	Fluoroquinolones	Ciprofloxacin or levofloxacin
	Third-generation cephalosporins	Ceftriaxone or cefotaxime and ceftazidime
	Macrolides	Azithromycin
Neisseria gonorrhoeae	Third-generation cephalosporins	Cefixime
		Ceftriaxone
	Macrolides	Azithromycin
	Aminocyclitols	Spectinomycin
	Fluoroquinolones	Ciprofloxacin
	Aminoglycosides	Gentamicin

^aThe listed substances are priorities for surveillance of resistance in each pathogen, although they may not be first-line options for treatment. One or more of the drugs listed may be tested.

^bOne or more of the drugs listed may be tested in countries. S, I, R and nominator and denominator data for each shall be reported separately.

^cImipenem or meropenem is preferred to represent the group when available.

^dCefoxitin is a surrogate for testing susceptibility to oxacillin (methicillin, nafcillin); the AST report to clinicians should state susceptibility or resistance to oxacillin.

^eOxacillin is a surrogate for testing reduced susceptibility or resistance to penicillin; the AST report to clinicians should state reduced susceptibility or resistance to penicillin.