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. Author manuscript; available in PMC: 2017 Jun 15.
Published in final edited form as: Int J Artif Organs. 2016 Mar 30;39(4):150–159. doi: 10.5301/ijao.5000478

Figure 2.

Figure 2

(A) Blood of a calf implanted with a CAD (high RBC aggregation and high plasma fibrinogen concentration); (B) Blood of a control calf (no RBC aggregation and low fibrinogen concentration); (C) Control RBCs placed in the CAD animal’s plasma (no RBC aggregation at high fibrinogen concentration); and (D) CAD calf RBCs placed in the control calf plasma (high RBC aggregation despite low fibrinogen concentration) (43). The aggregation present in frames (A) and, especially, (D) indicate that there are RBC-specific changes directly induced by mechanical stress related to CAD support. Reprinted with permission from IOS Press (43).