Table 3.
Variable | Intra-abdominal Recurrence Rate at 5-year, % |
Intra-abdominal Recurrence P Value |
DMFS 5-year rate, % |
DMFS P value |
---|---|---|---|---|
Age | ||||
> 65 | 62 | 0.047 | 73 | 0.48 |
≤ 65 | 40 | 68 | ||
Tumor Size | ||||
> 5 cm | 42 | 0.13 | 70 | 0.51 |
≤ 5 cm | 65 | 62 | ||
De Novo at presentation | ||||
Yes | 31 | <0.001 | 66 | 0.28 |
No | 76 | 78 | ||
Histology | ||||
Liposarcoma | 54 | 0.008 | 84 | 0.08 |
Other | 39 | 61 | ||
Grade | ||||
High | 46 | 0.32 | 60 | 0.003 |
Intermediate | 40 | 81 | ||
Low | 41 | 94 | ||
Margin Status | ||||
Positive/Uncertain | 58 | 0.003 | 70 | 0.86 |
Negative | 30 | 68 | ||
Treatment Plan | ||||
Preop RT | 44 | 0.60 | 70 | 0.62 |
Postop RT | 47 | 68 | ||
Radiation Dose | ||||
> 50 Gy | 43 | 0.85 | 67 | 0.71 |
≤ 50 Gy | 49 | 57 | ||
IORT | ||||
Yes | 44 | 0.82 | 67 | 0.46 |
No | 45 | 70 | ||
Neo or Adj. Chemo | ||||
Yes | 37 | 0.38 | 71 | 0.98 |
No | 51 | 67 | ||
Concurrent Chemoradiation | ||||
Yes | 45 | 0.96 | 50 | 0.02 |
No | 44 | 72 |
Abbreviations: DMFS, distant metastatic free survival; RT, radiation therapy; IORT, intraoperative radiation therapy; Neo/Adj, neoadjuvant/adjuvant.