Table 3.
Univariate Analysis of Factors Potentially Affecting Actuarial Rates of Intra-abdominal Recurrence and Distant Metastatic Free Survival Rates at 5 years
| Variable | Intra-abdominal Recurrence Rate at 5-year, % |
Intra-abdominal Recurrence P Value |
DMFS 5-year rate, % |
DMFS P value |
|---|---|---|---|---|
| Age | ||||
| > 65 | 62 | 0.047 | 73 | 0.48 |
| ≤ 65 | 40 | 68 | ||
| Tumor Size | ||||
| > 5 cm | 42 | 0.13 | 70 | 0.51 |
| ≤ 5 cm | 65 | 62 | ||
| De Novo at presentation | ||||
| Yes | 31 | <0.001 | 66 | 0.28 |
| No | 76 | 78 | ||
| Histology | ||||
| Liposarcoma | 54 | 0.008 | 84 | 0.08 |
| Other | 39 | 61 | ||
| Grade | ||||
| High | 46 | 0.32 | 60 | 0.003 |
| Intermediate | 40 | 81 | ||
| Low | 41 | 94 | ||
| Margin Status | ||||
| Positive/Uncertain | 58 | 0.003 | 70 | 0.86 |
| Negative | 30 | 68 | ||
| Treatment Plan | ||||
| Preop RT | 44 | 0.60 | 70 | 0.62 |
| Postop RT | 47 | 68 | ||
| Radiation Dose | ||||
| > 50 Gy | 43 | 0.85 | 67 | 0.71 |
| ≤ 50 Gy | 49 | 57 | ||
| IORT | ||||
| Yes | 44 | 0.82 | 67 | 0.46 |
| No | 45 | 70 | ||
| Neo or Adj. Chemo | ||||
| Yes | 37 | 0.38 | 71 | 0.98 |
| No | 51 | 67 | ||
| Concurrent Chemoradiation | ||||
| Yes | 45 | 0.96 | 50 | 0.02 |
| No | 44 | 72 |
Abbreviations: DMFS, distant metastatic free survival; RT, radiation therapy; IORT, intraoperative radiation therapy; Neo/Adj, neoadjuvant/adjuvant.