Table 2.
Summary of vaccine-induced effects compared with VSV*ΔG.
| VSV*ΔG_HA | VSV*ΔG_NA | WIV | |
|---|---|---|---|
| Body temperature | None | None | P = 0.019 |
| Macroscopical lung lesions | Reduction | None | Reduction |
| Histological lung lesions | Reduction | None | None |
| Viral RNA loads in swabs | Reduction | None | None |
| Viral RNA loads in BAL | Reduction | None | None |
| Viral RNA loads in lung tissue | None | None | None |
| IFNα in serum | Reduction | None | None |
| IFNα in BAL | None | None | None |
| IL-6 in lung tissue | Reduction | None | None |
| IL-1β in lung tissue | Reductiona | None | None |
aWhen compared with VSV*ΔG_NA; p = 0.04.