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. 2016 Jun 17;57(7):3257–3267. doi: 10.1167/iovs.15-18993

Figure 5.

Figure 5

Gene Lcn2 expression in Mertk−/− murine model of retinitis pigmentosa. (A) Representative SD-OCT shows age-related retinal degeneration in Mertk−/− mice. Images were obtained from the inferior retina at 500 to 750 μm from the ONH. (B) Outer nuclear layer thickness measured by SD-OCT is presented (n = 4 for each group). Error bars: Mean ± SD. (C) Quantitative RT-PCR revealed 8.8- or 4.5-fold increased Lcn2 expression in the eye at 3 or 6 months of age compared to that of 3 weeks coinciding with onset of retinal degeneration in Mertk−/− mice. *P < 0.05 vs. 3-week-old mice (n = 4 for each group).