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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Prostate. 2015 Sep 18;75(16):1941–1950. doi: 10.1002/pros.23093

Figure 2.

Figure 2

PCa and adjacent benign tissue have distinct DNA methylation profiles. A, heat map of DNA methylation levels in PCa (red) and adjacent benign tissue (green), based on unsupervised clustering. The 2,040 differentially methylated CpGs in PCa versus benign tissue (FDR Q-value <0.001) were used as input. The rows represent the tissue samples and the columns the CpG sites. Each sample is represented by a unique code, which consist of the patient ID (1 to 20) followed by the letter B (benign prostate tissue) or C (PCa tissue). Methylation M-values were used to construct the heat map. B, characteristics of patients in the study. The corresponding patient IDs are shown in the heat map. Abbreviations: PSA, prostate-specific antigen; EA, European-American; AA, African-American.

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