Table 1. Study Definitions.

Term	Definition
Active HCP Time	Time actively dedicated by any staff member on pre-specified tasks.
Observed Time	Time collected through stopwatch measurement for pre-specified tasks related to the rituximab preparation (IV reconstitution or SC syringe filling), dispensing, treatment administration and post-treatment monitoring.
Chair Time	Time between entry and exit of patient chair.*
Treatment Room	The place where IV and SC rituximab treatments are being administered.
Patient Treatment Room Time	Time between entry in treatment room for receiving rituximab therapy and exit of treatment room.
DPA	The place where IV rituximab reconstitution and SC hand-held syringe filling is typically performed, prior to the actual treatment administration. The DPA can refer to the hospital pharmacy or to a special aseptic DPA within the day oncology unit.

*In the case of induction therapy, with same-day concomitant infusion(s), exit time was adjusted to reflect the time when activities related to rituximab were completed.

HCP: healthcare professional; IV: intravenous; SC: subcutaneous; DPA: drug preparation area.