Skip to main content
. 2016 Jun 30;11(6):e0157563. doi: 10.1371/journal.pone.0157563

Table 5. Impact of the Number of Abnormal ECG Categories on All-Cause and Cardiovascular Death in Women.

All-Cause Death Cardiovascular Death Coronary Death Stroke Death
(1,796 events) (623 events) (120 events) (266 events)
N (%) HR (95%CI) P value HR (96%CI) P value HR (97%CI) P value HR (98%CI) P value
FRS Adjusted HRs
    No abnormality 7,719 (80) Reference Reference Reference Reference
    Single abnormality 1,654 (17) 1.63 (1.46, 1.81) <0.001 1.72 (1.43, 2.05) <0.001 1.80 (1.21, 2.70) 0.004 1.65 (1.25, 2.17) <0.001
    ≥2 Abnormalities 273 (3) 3.03 (2.53, 3.62) <0.001 4.83 (3.76, 6.22) <0.001 5.15 (2.94, 9.02) <0.001 4.78 (3.25, 7.06) <0.001
NDRC Adjusted HRs
    No abnormality 7,471 (80) Reference Reference Reference Reference
    Single abnormality 1,612 (17) 1.31 (1.18, 1.46) <0.001 1.33 (1.11, 1.60) 0.002 1.47 (0.98, 2.20) 0.06 1.23 (0.93, 1.63) 0.152
    ≥2 Abnormalities 265 (3) 1.37 (1.15, 1.66) 0.001 2.04 (1.58, 2.64) <0.001 2.32 (1.31, 4.12) 0.004 2.01 (1.35, 2.98) 0.001

FRS: Framingham risk score was calculated using age, gender, body mass index, systolic blood pressure, diabetes mellitus, and current smoking. NDRC: Risk probability using the NIPPON DATA80 risk chart was calculated using age, gender, systolic blood pressure, total cholesterol level, diabetes mellitus, and current smoking. Gender was not accounted for in calculation of the FRS and the NDRC as only men were analyzed.