Table 6. Examples of behavior/neural-related ‘Eutheria-conserved’ Alarm_Pheromone Genes’ Human Orthologs(Part 2).
| Entrez ID | Name | GO Terms related | Neural Disease/behavior related |
|---|---|---|---|
| 3312 | HSPA8 | GO:0006457~protein folding,GO:0006950~response to stress,GO:0006986~response to unfolded protein,GO:0044237~cellular metabolic process,GO:0051789~response to protein stimulus | neurocognitive and behavioral defects(PMID: 18855024,PMID: 21056629(behavioral study in mice, not directly causative)) |
| 84246 | MED10 | GO:0044237~cellular metabolic process | neurodegeneration(PMID: 18929508,indirectly related) |
| 8879 | SGPL1 | GO:0044237~cellular metabolic process | neurodegeneration(PMID: 21331079) |
| 645 | BLVRB | GO:0044237~cellular metabolic process | neurodegeneration(PMID: 7682296,PMID: 8845972) |
| 9374 | PPT2 | GO:0044237~cellular metabolic process | neuronal ceroid lipofuscinosis(PMID: 10051407) |
| 5683 | PSMA2* | GO:0044237~cellular metabolic process | Parkinson(PMID: 21069393,PMID: 15455214) |
| 478 | ATP1A3 | GO:0044237~cellular metabolic process | parkinsonism(PMID: 17282997) |
| Alzheimer's disease(PMID: 2035524) | |||
| Depression(PMID: 18068248) | |||
| 1460 | CSNK2B | GO:0006950~response to stress,GO:0006986~response to unfolded protein,GO:0051789~response to protein stimulus | Parkinson's disease(GeneCard Inferred) |
| 4709 | NDUFB3 | GO:0044237~cellular metabolic process | Parkinson's disease(PMID: 17211632) |
| 3301 | DNAJA1 | GO:0006457~protein folding,GO:0006950~response to stress,GO:0006986~response to unfolded protein,GO:0044237~cellular metabolic process,GO:0051789~response to protein stimulus | Parkinson's disease(PMID: 22343013) |
| 7334 | UBE2N | GO:0006950~response to stress,GO:0044237~cellular metabolic process | schizophrenia(PMID: 12363385,PMID: 20109112) |
| 11080 | DNAJB4 | GO:0006457~protein folding,GO:0006950~response to stress,GO:0006986~response to unfolded protein,GO:0044237~cellular metabolic process,GO:0051789~response to protein stimulus | stress-related(PMID: 24511526) |
Based on the Gene Ontology result of Eutheria-conserved’ Alarm_Pheromone Genes’ Human Orthologs, genes related to the significant biological process GO terms(Benjamini p-value ≤ 0.05) are presented here.