Table 6. Significantly different channels and corresponding brain regions presented in temporal changes of [oxy-Hb].

1. Tooth Loss vs. Wearing Denture
	Pre-chewing	Chewing	Post-chewing
DLPFC	ch. 6, 10	ch. 1, 2, 3, 4, 6, 8, 10, 13	ch. 1, 2, 3, 4, 6, 8, 10
FPA	ch. 6, 10	ch. 6, 7, 8, 10, 11, 12, 13, 15	ch. 6, 7, 8, 10, 12, 15
BA	ns	ch. 5	ch. 5
OFC	ns	ch. 15	ch. 15
IPG	ns	ns	ns
2. Tooth Loss vs. Young
	Pre-chewing	Chewing	Post-chewing
DLPFC	ns	ch. 1, 2, 4, 6, 10	ch. 1, 2, 6, 10
FPA	ch. 15	ch. 6, 10, 11, 12, 15	ch. 6, 10
BA	ns	ch. 5	ch. 5
OFC	ch. 15	ch. 15	ns
IPG	ns	ns	ns
3. Wearing Denture vs. Young
	Pre-chewing	Chewing	Post-chewing
DLPFC	ns	ch. 1, 6	ch. 6
FPA	ns	ch. 6	ch. 6
BA	ns	ch. 5	ns
OFC	ns	ns	ns
IPG	ns	ns	ns

The channels shown presented significantly (Bonferroni t-test, p<0.05) changed values for [oxy-Hb] between Tooth Loss and Wearing Denture, Tooth Loss and Young, and Wearing Denture and Young. During the chewing period under both the Young and Wearing Denture conditions, there was a large number of activated channels in the prefrontal cortex as compared with Tooth Loss, while there were few activated channels in the prefrontal cortex during that period under the Wearing condition as compared with Young.