Table 2. Association of BMP2 SNPs and risk of mandibular incisor agenesis.
| Genotype | Controls | Mandibular incisor agenesis | Pattern | Pa | OR (95% CI) b |
|---|---|---|---|---|---|
| N = 444 (%) | N = 194 (%) | ||||
| rs15705 (A > C) | AC vs. AA | 0.503 | 0.87 [0.58–1.31] | ||
| AA | 120 (27.2) | 52 (26.8) | CC vs. AA | 0.131 | 1.44 [0.90–2.31] |
| AC | 236 (53.5) | 89 (45.9) | AC / CC vs. AA | 0.915 | 1.02 [0.70–1.50] |
| CC | 85 (19.3) | 53 (27.3) | AA / AC vs. CC | 0.024 | 1.58 [1.06–2.34] |
| C/A allele | 406 (46.0)/ 476 (54.0) | 195 (50.3)/ 193 (49.7) | A vs. C | 0.165 | 1.19 [0.93–1.50] |
| rs3178250 (T > C) | TC vs. TT | 0.528 | 0.88 [0.59–1.32] | ||
| TT | 121 (27.5) | 52 (26.8) | CC vs. TT | 0.111 | 1.47 [0.92–2.36] |
| TC | 236 (53.5) | 89 (45.9) | TC / CC vs. TT | 0.869 | 1.03 [0.71–1.51] |
| CC | 84 (19.0) | 53 (27.3) | TT / TC vs. CC | 0.020 | 1.60 [1.08–2.37] |
| C / T allele | 404 (45.8)/ 478 (54.2) | 195 (50.3)/ 193 (49.7) | T vs. C | 0.143 | 1.20 [0.94–1.52] |
a Two-sided chi-square test
b OR, odds ratio; 95% CI, 95% confidence interval.