Table 1. Main characteristics of the cohort.
| Variable | Cases (n = 67) COPD | Controls (n = 67) Smokers, non-COPD | P |
|---|---|---|---|
| Age, yr | 59·4 ± 5·9 | 58·2 ± 6·9 | 0·28 |
| Males, n, % | 52 (77·6%) | 52 (77·6%) | - |
| Charlson index | 2·0± 1·2 | 0·7 ± 0·9 | < 0·0001 |
| Modified Charlson index* | 0·9 ± 1·1 | 0·7 ± 0·9 | 0·14 |
| Active smokers, n, % | 34 (50·7%) | 47 (70·1%) | 0·001 |
| Pack-years | 52·7 ± 24·4 | 43·7 ± 26·9 | 0·01 |
| Alcohol intake > 80 gr/d, n, % | 10 (14·9%) | 9 (13·4%) | 1·00 |
| Treatment for hypertension, n, % | 29 (43·2%) | 25 (37·3%) | 0·59 |
| Treatment for dyslipidemia, n, % | 16 (23·8%) | 24 (35·8%) | 0·18 |
| Treatment for diabetes, n, % | 9 (13·4%) | 13 (19·4%) | 0·48 |
| Anticoagulation, n, % | 3 (4·4%) | 0 | 0·24 |
| Antiaggregation, n, % | 18 (26·8%) | 16 (23·9%) | 0·84 |
| Chronic bronchitis, n, % | 44 (65·6%) | 23 (34·3%) | 0·0005 |
| Dyspnea mMRC | < 0·0001 | ||
| mMRC class 0, n, % | 10 (14·9%) | 38 (56·7%) | |
| mMRC class 1, n, % | 29 (43·2%) | 23 (34·3%) | |
| mMRC class 2, n, % | 24 (35·8%) | 6 (8·9%) | |
| mMRC class 3, n, % | 4 (5·9%) | 0 | |
| mMRC class 4, n, % | 0 | 0 | |
| Snoring n,% | 33 (49·2%) | 30 (44·7%) | 0·79 |
| Epworth value | 3·2 ± 2·1 | 3·7 ± 2·7 | 0·61 |
| BMI, Kg/m2 | 27·7 ± 4·5 | 29·4 ± 4·5 | 0·03 |
| Abdominal perimeter, cm | 100·4 ± 12·2 | 100·3 ± 12·3 | 0·96 |
| FEV1% | 58·4 ± 20·7 | 96·6 ±15·8 | < 0·0001 |
| FVC % | 82·4 ± 16·8 | 94·5 ± 13·6 | < 0·0001 |
| FEV1/FVC % | 51·3 ± 12·3 | 77·1 ± 4·3 | < 0·001 |
mMRC: modified medical research council; BMI: body mass index.
*In the modified Charlson index, COPD does not score.