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. 2016 Jun 30;11(6):e0158764. doi: 10.1371/journal.pone.0158764

Table 3. Comparison of mean HbA1c and fasting glucose according to 25(OH)D quartiles.

25(OH)D level Model 1 Model 2 Model 3
Mean (95% CI) Mean (95% CI) Mean (95% CI)
Fasting glucose (mg/dL) Quartile 1 145.1(140.2–150.0) 144.4 (139.5–149.3) 144.7 (139.7–149.7)
Quartile 2 144.4(139.7–149.2) 144.8 (140.1–149.5) 145.1 (140.4–149.8)
Quartile 3 142.7(138.1–147.4) 144.1 (139.5–148.7) 143.9 (139.3–148.4)
Quartile 4 142.7(137.8–147.7) 143.6 (138.7–148.4) 143.0 (138.1–147.9)
p for trend 0.468 0.787 0.608
p for between groups 0.893 0.988 0.945
Hemoglobin A1c (%) Quartile 1 7.48 (7.32–7.64)* 7.45 (7.29–7.61) 7.47 (7.30–7.63)*
Quartile 2 7.20 (7.04–7.36) 7.24 (7.08–7.39) 7.25 (7.09–7.40)
Quartile 3 7.13 (6.98–7.29) 7.18 (7.03–7.33) 7.17 (7.02–7.32)
Quartile 4 7.19 (7.03–7.36) 7.20 (7.05–7.36) 7.19 (7.02–7.35)
p for trend 0.018 0.043 0.021
p for between groups 0.018 0.083 0.050

Model 1, Adjusted by month of blood collection, sex and age

Model 2, Adjusted by Model 1 plus BMI, smoking, physical activity, hypertension medications, diabetic duration, total cholesterol, triglyceride and HDL cholesterol

Model 3, Adjusted by Model 2 plus log-PTH

*p<0.005 compared with Quartile 3 with the Bonferroni adjustment for multiple comparison