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. 2016 Jun 17;2(6):e1501678. doi: 10.1126/sciadv.1501678

Table 5. Fine-mapping of the DLEU1 locus.

MAF (controls in %) and r2 (with rs2812197) are calculated from a joint set of DE1 and DE2, ORs and P values from the pooled analysis of DE1 and DE2. Second and third P value columns are from conditional analysis.

Variant MAF OR (CI) P P (rs2812197) P (rs9591325) r2 Reference
rs2812197 38.4 0.86 (0.82–0.91) 9.95 × 10−9 4.79 × 10−5 1.00
rs806321 48.5 0.89 (0.85–0.94) 6.36 × 10−6 0.81 2.02 × 10−3 0.66 (5)
rs806349 46.0 1.10 (1.04–1.15) 2.73 × 10−4 0.99 0.019 0.41 (4, 21)
rs9591325 8.1 0.78 (0.70–0.85) 2.26 × 10−7 9.13 × 10−4 0.14
rs9596270 8.1 0.78 (0.71–0.86) 4.45 × 10−7 1.49 × 10−3 0.27 0.14 (0.99*) (6)

*r2 with rs9591325.