TABLE 2.
LIST OF ANTAGONISTS AND INHIBITORS
| Antagonist | Synonym | Dose (s) | Target |
|---|---|---|---|
| Caffeine | 1,3,7-Trimethylxanthine | 50, 100, 200 µM | A1 > A2 > A3 |
| DPCPX | 1,3-Dipropyl-8cyclopentylxanthine | 10 nM | A1 |
| MRS1220 | 9-Chloro-2-(2-furanyl)-5-(phenylacetyl amino)-[1,2,4]triazolo[1,5-c] quinazoline | 10 nM | A3 |
| RO-201724 | 4- (3- Butoxy- 4- methoxybenzyl)- 2- imidazolidinone | 10 µM | PDE IV |
| RP-cAMPs | Rp-Adenosine 3′,5′-cyclic monophosphorothioate triethylammonium salt hydrate | 50 µM | cAMP-PKA |
A1, A2a, A2b, A3, adenosine receptor subtypes; cAMP, cyclic adenosine monophosphate; PDE, phosphodiesterase; PKA, protein kinase A