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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Transl Stroke Res. 2016 Mar 20;7(4):322–330. doi: 10.1007/s12975-016-0462-x

Fig 1. Functional improvement in mice treated with whole MNCs and MNCs depleted of specific sub-populations of cells via IV at 24 hrs after stroke.

Fig 1

Mice were assigned to 6 treatment groups: 1) saline; 2) whole MNCs; 3) MNCs with Lymphoid cell depletion; 4) MNCs with Myeloid cell depletion; 5) MNCs with Erythroid lineage cell depletion; 6) MNCs with stem cell and progenitor cell depletion. Line diagrams illustrating evaluation on the Cylinder (A) and Ladder run (B) tests up to 28 days after stroke. Data are mean ± SD; N= 12 per group initially but only 6 survived to the end of observation and all mice with myeloid cell depleted MNCs died within 9 days after stroke. *P < 0.05, compared with saline controls. The bar graph (C) exhibiting significantly reduced cerebral atrophy among the same experimental groups at 28 days after stroke. Data are mean ± SD. N= 6 per group. *P < 0.05 compared with saline controls.