Skip to main content
. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):200–209. doi: 10.1097/MPG.0000000000001100

Figure 5. Fibroblast traction force increases with matrix stiffness.

Figure 5

Fibroblasts were seeded on micropost arrays (post diameter = 1.83 μm) with varying post height, thereby varying the spring constant of the post and stiffness of the matrix. Representative images of fibroblasts seeded on 5kPa and 20kPa mPADs (A). Fibroblasts from all phenotypes exerted similar tensile force of engaged microposts of the same stiffness (NS) (B). Traction forces generated by fibroblasts on soft (5kPa) and stiff (20kPa) posts (C). * p<0.0001