Table 3.

MSAS and FACT Subscales^[1]

Subscales	Baseline	Month 3	Month 6	Month 9	Month 12	P value
Physical symptom*	0.4732 (0.02473)	0.4291 (0.02322)	0.4073 (0.02151)	0.4058 (0.02319)	0.4021 (0.02199)	0.0057
Psychological symptom	0.7567 (0.03654)	0.7520 (0.03779)	0.7326 (0.03635)	0.7050 (0.03720)	0.6904 (0.03675)	0.1651
Global distress index	0.6979 (0.03232)	0.6650 (0.03235)	0.6331 (0.03052)	0.6310 (0.03163)	0.6331 (0.03085)	0.0710
Total MSAS*	0.5346 (0.02239)	0.4979 (0.02186)	0.4726 (0.02057)	0.4724 (0.02168)	0.4704 (0.02112)	0.0012
# of symptoms*	8.9447 (0.3336)	8.1748 (0.3150)	8.4362 (0.3234)	8.0409 (0.3130)	8.0483 (0.3088)	0.0066
FACT-G: physical QOL**	23.5494 (0.2250)	24.3060 (0.1959)	24.2046 (0.1975)	24.3833 (0.1975)	24.2197 (0.2001)	<0.0001
FACT-G: social QOL	21.2829 (0.2591)	20.9131 (0.2771)	20.6996 (0.2913)	20.8543 (0.2876)	20.7523 (0.2854)	0.0711
FACT-G: emotional QOL	19.6773 (0.1694)	19.7248 (0.1732)	19.9268 (0.1627)	19.8727 (0.1651)	19.6612 (0.1809)	0.1713
FACT-G: functional QOL	20.9203 (0.2710)	21.0281 (0.2789)	20.7534 (0.2979)	20.9793 (0.2936)	21.0321 (0.2802)	0.7641
FACT-G: overall QOL	85.3746 (0.7197)	85.7755 (0.7276)	85.3983 (0.7451)	85.9918 (0.7435)	85.5660 (0.7559)	0.6785

^*p<.01

^**p<.001

^[1]Least square means and standard error