Fig. 2.
Plasma paclitaxel concentrations at 24 and 28 h. a Patients 1, 3, 7, and 8 were randomized to placebo/nab-paclitaxel during C1. Patients 1, 7, and 8 had no significant increase in paclitaxel levels when treated with mifepristone/nab-paclitaxel in C2. However, patient 3 had higher paclitaxel levels in C2 when treated with mifepristone/nab-paclitaxel. b patients treated at dose level 1 (nab-paclitaxel 100 mg/m2) had higher plasma paclitaxel concentrations than those patients treated at dose level −1 (nab-paclitaxel 80 mg/m2). C1 cycle 1, C2 cycle 2