Table 3.
Concentrations of pro- and anti-inflammatory mediators between the young (n = 10) and older (n = 40) participants. Values are pg/ml unless stated otherwise and data are mean ± SEM.
| Young | Old |
|||
|---|---|---|---|---|
| All | MA (n = 20) | LA (n = 20) | ||
| Pro-Inflammatory | ||||
| IL-1β (pg/ml)a | 0.21 ± 0.05 | 0.33 ± 0.04 | 0.31 ± 0.05 | 0.35 ± 0.07 |
| IL-6 (pg/ml)a | 1.36 ± 0.92 | 5.11 ± 1.49# | 5.71 ± 2.27 | 4.46 ± 1.99 |
| IL-8 (pg/ml) | 5.63 ± 0.58 | 6.79 ± 0.30# | 6.49 ± 0.32 | 7.11 ± 0.51 |
| IL-17 (pg/ml)a | 10.09 ± 10.09 | 16.01 ± 6.55 | 17.40 ± 11.33 | 14.48 ± 6.13 |
| TNFα (pg/ml)a | 0.23 ± 0.11 | 3.99 ± 2.47 | 5.36 ± 4.40 | 2.48 ± 1.96 |
| CRP (mg/L)a | 1.30 ± 0.81 | 2.13 ± 0.45# | 2.46 ± 0.81 | 1.77 ± 0.29 |
| GM-CSF (pg/ml)a | ND | 2.13 ± 1.52 | 2.44 ± 2.44 | 1.79 ± 1.79 |
| MCP-1 (pg/ml) | 27.63 ± 2.44 | 43.84 ± 2.57## | 43.31 ± 3.84# | 44.42 ± 3.44# |
| Anti-Inflammatory | ||||
| IL-4 (pg/ml)a | ND | 0.01 ± 0.01 | 0.02 ± 0.01 | 0.01 ± 0.01 |
| IL-10 (pg/ml)a | 7.12 ± 3.12 | 19.34 ± 3.45## | 17.33 ± 4.67 | 21.56 ± 5.19# |
| IL-13 (pg/ml) | 4.13 ± 1.20 | 7.15 ± 0.71# | 6.29 ± 0.87 | 8.10 ± 1.14 |
ND (not-detectable); IL (Interleukin); TNFα (tumour necrosis factor-α); CRP (C-Reactive Protein); GM-CSF (Granulocyte/Monocyte Colony Stimulating Factor); MCP-1 (Monocyte Chemoattractant Protein-1). aNot normally distributed and log-transformed. #p < 0.05 and ##p < 0.01 compared to young group.