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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Immunol. 2016 May 20;197(1):288–295. doi: 10.4049/jimmunol.1501946

FIGURE 3.

FIGURE 3

Dysfunction in the GP Ib-IX-GEMs association delays the formation of a FeCl3-induced thrombus in the carotid artery. A. Murine right common carotid artery was exposed to a 10×10 mm strip of 3MM Waterman filter paper saturated in a 10% FeCl3 solution (upper panel). The blood flow and ECG signals were monitored using a PC-based high-speed real-time Doppler signal processing system (lower panel). The occlusion time was counted as the period from the removal of the filter paper to the time when the Doppler signal went to nearly zero. B. The average occlusion time for the wild-type mice (HαWT, n=8) was approximately ~1min shorter than that for the mutant animals (HαSS, n=14). C. Mouse tail bleeding time was defined as the time from incision to cessation of blood.