Table 3. Comparison of mean inflammatory markers between obese and non-obese patients in T allele carriers and CC genotype.
Variable | IL-18, pg/mL | PTX3, ng/mL | hs-CRP, mg/L |
---|---|---|---|
TT+TC (n=120) | |||
Obese | 254.56±35.64 | 2.59±0.38 | 2.28±1.22 |
Non-obese | 242.37±27.69 | 2.76±0.52 | 1.55±1.37 |
Mean difference (95% CI) | -12.19 (-23.77 to -0.61) | 0.17 (0.003 to 0.33) | -0.72 (-1.19 to -0.25) |
P valuea | 0.03 | 0.04 | 0.003 |
P valueb | 0.12 | 0.50 | 0.01 |
CC (n=60) | |||
Obese | 256.31±25.79 | 2.44±0.51 | 3.06±1.61 |
Non-obese | 245.10±28.49 | 2.59±0.37 | 2.59±1.69 |
Mean difference (95% CI) | -10.68 (-24.63 to 3.25) | 0.15 (-0.07 to 0.38) | -0.46 (-1.31 to 0.38) |
P valuea | 0.13 | 0.19 | 0.27 |
P valueb | 0.41 | 0.53 | 0.29 |
Values are presented as mean±standard deviation.
IL-18, interleukin 18; PTX3, pentraxin 3; hs-CRP, high-sensitivity C-reactive protein; CI, confidence interval.
aUsing the independent t-test, bAdjusted for waist circumference, age, sex, and monounsaturated fatty acid using the analysis of covariance.