Table 1. Baseline characteristics.
Characteristic | Vildagliptin 50 mg bid+metformin | Pioglitazone 15 mg qd+metformin | P value |
---|---|---|---|
Age, yr | 55.2±9.8 | 53.9±9.1 | 0.293 |
Sex | 0.938 | ||
Male | 50 (42.7) | 48 (43.2) | |
Female | 67 (57.3) | 63 (56.8) | |
Body weight, kg | 65.00±11.29 | 64.87±11.56 | 0.937 |
Body mass index, kg/m2 | 24.9±3.2 | 25.0±3.3 | 0.769 |
Disease duration, mo | 68.3±62.0 | 60.2±58.6 | 0.316 |
Glycosylated hemoglobin, % | 7.98±0.77 | 8.08±0.98 | 0.389 |
Fasting plasma glucose, mg/dL | 147.8±38.6 | 151.3±35.5 | 0.480 |
Postprandial glucose, mg/dL | 274.9±73.8 | 268.4±80.9 | 0.530 |
Triglyceride, mg/dL | 142.8±69.7 | 144.7±68.8 | 0.836 |
Total cholesterol, mg/dL | 170.0±34.5 | 173.9±34.9 | 0.409 |
LDL-C, mg/dL | 98.0±28.7 | 100.2±32.0 | 0.594 |
HDL-C, mg/dL | 46.3±11.8 | 48.3±11.6 | 0.214 |
Non-HDL-C, mg/dL | 123.9±32.1 | 125.2±34.7 | 0.769 |
Values are presented as mean±standard deviation or number (%).
bid, twice daily; qd, once daily; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol.