Table 1.
Characteristics of the participants in the study
| Patients | Controls | P value | |
|---|---|---|---|
| No. of participants (n) | 600 | 300 | ― |
| Gender, Male (n) | 432 | 205 | 0.254 |
| Age (years, mean ± S.D.) | 62.1 ± 6.7 | 61.7 ± 6.9 | 0.410 |
| Ethnic group, Han (n) | 574 | 288 | 0.815 |
| Smoking history | |||
| Current smoking (n) | 335 | 151 | 0.119 |
| Former smoking (n) | 106 | 68 | 0.073 |
| Non‐smoking (n) | 159 | 81 | 0.873 |
| CYP2C19*2 genotype | |||
| GG (n, %) | 287 (47.8) | 174 (58.0) | 0.004 |
| GA (n, %) | 225 (37.5) | 113 (37.7) | 0.961 |
| AA (n, %) | 88 (14.7) | 13 (4.3) | 0.000 |
GG: CYP2C19 681 wild‐type homozygotes; GA: CYP2C19 681 mutant heterozygotes; AA: CYP2C19 681 mutant homozygotes.