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. 2016 Mar 17;20(7):1381–1391. doi: 10.1111/jcmm.12828

Figure 5.

Figure 5

Effects of Feno on cardiomyocyte apoptosis in siRNA‐1186‐treated cardiomyocytes. (A) The SCAD mRNA expression was significantly decreased in cardiomyocytes treated with siRNA‐1186, however, increased in cardiomyocytes pre‐treated with Feno. (B) The SCAD protein expression was significantly decreased in cardiomyocytes treated with siRNA‐1186, however, increased in cardiomyocytes pre‐treated with Feno. (C) The SCAD enzyme activity was significantly decreased in cardiomyocytes treated with siRNA‐1186, however, increased in cardiomyocytes pre‐treated with Feno. (D) The content of free fatty acid was significantly increased in cardiomyocytes treated with siRNA‐1186, however, decreased in cardiomyocytes pre‐treated with Feno. (E) The ATP level was significantly decreased in cardiomyocytes treated with siRNA‐1186, however, increased in cardiomyocytes pre‐treated with Feno N‐C: negative control siRNA. Mean ± S.D., n = 3, *P < 0.05, **P < 0.01 versus control, #P < 0.05, ##P < 0.01 versus si‐1186.