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. 2016 Mar 17;20(7):1381–1391. doi: 10.1111/jcmm.12828

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© 2016 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The protective effects of Feno on cardiomyocyte apoptosis induced by siRNA‐1186. (A) The derease of cell viability were abrogated in siRNA‐1186 group pre‐treated with Feno. (B and C) The cell apoptotic rate was increased significantly in siRNA‐1186 group, however, decreased in cardiomyocytes pre‐treated with Feno. (D) Cell apoptosis was determined with Hoechst 33258 staining. 200× magnification. (E) Effects of Feno on the expression of apoptosis‐related proteins in siRNA‐1186‐induced cardiomyocytes. N‐C: negative control siRNA. Mean ± S.D., n = 3, *P < 0.05, **P < 0.01 versus control, #P < 0.05, ##P < 0.01 versus si‐1186.