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. 2016 May 7;594(13):3561–3574. doi: 10.1113/JP271925

Figure 5. Afterdepolarization (ADP) properties in DRG neurons from WT and KI mice .

Figure 5

A, representative APs with ADP before and after application of zinc (1 and 30 μm) in D‐hair neurons of WT (left) and KI mice (right). The resting membrane potential of the neurons was maintained at −70 mV. B, ADP amplitude (in mV) in control condition is determined as the difference in voltage from the resting potential value (*P < 0.05; Mann‐–Whitney). C and D, effect of the application of zinc at 1 and 30 μm (C) and nickel at 30 μm (D) on ADP amplitude. Statistical analysis was performed with two‐way ANOVA followed by Sidak's test (*P < 0.05; ***P < 0.001; KI Ctrl vs. KI Zn 1 μm, P = 0.22; WT Ctrl vs. WT Ni 1 μm, P = 0.11; KI Ctrl vs. KI Ni 1 μm, P = 0.61; KI Ctrl vs. KI Ni 30 μm, P = 0.43).