Figure 6.

Pik3r1 (p85) regulates survivin expression after ileocecal resection (ICR). A: Quantitation of cells positive for survivin, bromodeoxyuridine (BrdU), and cleaved caspase-3 in the jejunum of p85^ΔIEC control, p85^ΔIEC sham, and p85^ΔIEC ICR mice. Counts for wild-type (WT) control mice are shown for reference. B and C: Real-time RT-PCR for mRNA expression of survivin and Dr5 in intestinal epithelial cells isolated from jejunum of WT control, p85^ΔIEC control, p85^ΔIEC sham, and p85^ΔIEC ICR mice. Data are shown as the means ± SEM (A–C). ^∗P < 0.05 versus p85^ΔIEC.