Table 1.
Patient Characteristics
| Site | Tissue analyzed | Age at first surgery (days) | Age at second surgery or harvest (days) | Interval (days) | Gestation (weeks) | Diagnosis |
|---|---|---|---|---|---|---|
| Ileum | Control | 12 | 45 | 33 | 23 | NEC at day 6, Penrose drain at day 12 for perforation |
| Ileum | Control | 3 | 76 | 73 | 29 | SIP |
| Ileum | Control | 1 | 42 | 42 | 33 | Gastroschisis and jejunal atresia |
| Ileum | Ostomy repair | 7 | 76 | 69 | 30 | NEC (10 cm removed) |
| Ileum | Ostomy repair | 4 | 61 | 57 | 27 | SIP (2 cm removed) |
| Ileum | Ostomy repair | 0 | 53 | 53 | Term | Gastroschisis with infarcted bowel |
| Ileum | Ostomy repair | 13 | 88 | 75 | 25 | NEC at day 14 |
| Ileum | Ostomy repair | 1 | 56 | 60 | Term | NEC at day 1 |
| Ileum | Ostomy repair | 180 | 252 | 72 | Term | Intestinal failure |
Surgical data from three control and six small-bowel resection (SBR; ostomy repair) patients. Control patient samples were from healthy tissue taken before resection. For SBR patients, the time to ostomy repair averaged 65 days. When noted in surgical records, resection length ranged between 2 and 10 cm.
NEC, necrotizing enterocolitis; SIP, spontaneous intestinal perforation.