Table 4. The ability of IL34-FS as a Diagnosis of Liver Fibrosis by ROC Analyses.

	IL34-FS
Significant Fibrosis (≥Stage 2)
AUC	0.86
Cutoff value	1.86
Sensitivity (%)	75.2
Specificity (%)	85.0
PPV (%)	88.0
NPV (%)	70.1
Predictive accuracy (%)	79.2
Advanced Fibrosis (≥Stage 3)
AUC	0.88
Cutoff value	2.02
Sensitivity (%)	81.7
Specificity (%)	79.4
PPV (%)	69.1
NPV (%)	88.5
Predictive accuracy (%)	80.2
Liver Cirrhosis (Stage 4)
AUC	0.91
Cutoff value	2.67
Sensitivity (%)	83.3
Specificity (%)	85.6
PPV (%)	51.0
NPV (%)	96.6
Predictive accuracy (%)	85.2

The cutoff values, sensitivity, and specificity were determined as described in Table 3. AUC, ROC, PPV, NPV, see Table 3. IL34-FS, interleukin34 based fibrosis score.