Table 1. Clinicopathological characteristics and miR-2861 expression in cervical cancer patients.
Clinicopathological factors | Number of cases (n = 57) (%) | Mean expression of miR-2861 (range) (2−△△CT ± SD) | P value |
---|---|---|---|
Age (years) | 0.543a | ||
<35 | 7 (12.3%) | 0.43 ± 0.30 (0.20–1.09) | |
≥35 | 50 (87.7%) | 0.51 ± 0.39 (0.08–1.71) | |
Tumor stge | 0.026a | ||
I B | 35 (61.4%) | 0.60 ± 0.43 (0.19–1.71) | |
IIA | 22 (38.8%) | 0.35 ± 0.17 (0.08–0.81) | |
Differentiation | 0.347a | ||
Well/Moderate | 49 (86.0%) | 0.53 ± 0.39 (0.14–1.71) | |
Poor | 8 (14.0%) | 0.34 ± 0.15 (0.08–0.55) | |
Tumor size (cm) | 0.213a | ||
<4 | 51 (89.5%) | 0.53 ± 0.39 (0.14–1.71) | |
≥4 | 6 (10.5%) | 0.30 ± 0.14 (0.08–0.46) | |
SCC (ng/ml) | 0.884a | ||
<4 | 49 (86.0%) | 0.51 ± 0.40 (0.08–1.71) | |
≥4 | 8 (14.0%) | 0.44 ± 0.20 (0.20–0.81) | |
Deep stromal invasion | 0.759a | ||
<2/3 | 33 (57.9%) | 0.51 ± 0.37 (0.08–1.71) | |
≥2/3 | 24 (42.1%) | 0.50 ± 0.38 (0.19–1.70) | |
Vsucular involvement | 0.222a | ||
Negative | 37 (64.9%) | 0.54 ± 0.39 (0.14–1.71) | |
Positive | 20 (35.1%) | 0.43 ± 0.34 (0.08–1.58) | |
Lymph node metastasis | 0.047a | ||
Negative | 43 (75.4%) | 0.56 ± 0.41 (0.14–1.71) | |
Positive | 14 (24.6%) | 0.32 ± 0.11 (0.08–0.47) |
aP value when expression levels were compared using the Mann - Whitney test.