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. 2015 Oct 12;35(25):3324–3334. doi: 10.1038/onc.2015.394

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Copyright © 2016 Macmillan Publishers Limited

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Reduced KLF12 levels result in increased lung tumour formation and decreased survival. (a) KLF12 knockdown results in increased HOP62 cells tumour formation. Luminescence was presented visually (left panel), and its quantification is shown in a histogram (right panel). The P-value was derived from Mann–Whitney test. (b) KLF12 knockdown results in increased A549 cells in the lung. Luminescence was quantified after tail-vein injection at set time points. Values were normalized at the 5-h time point. (c) The lung cancer data set from Bild et al.³⁰ was analysed using the R2 genomics analysis and visualization platform (http://hgserver1.amc.nl/cgi-bin/r2/main.cgi).