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. 2016 Jul 1;6:28979. doi: 10.1038/srep28979

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Copyright © 2016, Macmillan Publishers Limited

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Mouse skin wounds created by six millimetre punch biopsy, were treated either PBS (CTL) or M-CSF recombinant protein (M-CSF) or M-CSF neutralizing antibody (antibody) for nine days. Photos were taken and wound size was measured on day 0, day 5 and day10, respectively. Mice were sacrificed on day 10. Skin sections fixed by 10% formalin were stained with Hematoxylin and Eosin (H & E). (A) Skin wounds on different time point; (B) H & E staining. Scale bars, 100 μm; (C) Wound size in different time point.