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. 2016 May 30;12(1):36–48. doi: 10.46582/jsrm.1201006

Table 3: ADMSCs effect on acute renal injury, regenerative and chronicity scores in the outer stripe of the outer medulla of rat kidney after cisplatin (n = 5 in each group for each time subgroup; mean ± SD).

Control Cispl. Cispl.+ C.Medium Cispl.+ ADMSC
Necrotic tub.
4 0.0±0.0 12.6±2.1* 8.4±1.7* 3.9±0.3*°
7 0.0±0.0 8.6±1.3* 8.3±1.5* 4.6±0.4*°
11 0.0±0.0 7.4±1.8* 7.5±2.2* 2.6±0.2*°‡†
30 0.0±0.0 4.7±0.1*‡†• 2.4±0.3*‡†• 1.0±0.6*°‡†•
Inflam. cells
4 0.0±0.0 8.8±1.3* 8.4±1.6* 1.8±0.2*°
7 0.0±0.0) 8.4±1.6* 8.3±1.9* 1.5±0.3*°
11 0.0±0.0 8.5±1.1* 8.1±1.5* 0.0±0.0°‡†
30 0.0±0.0 4.7±0.2*‡†• 4.4±0.3*‡†• 0.0±0.0°‡†
Reg. Tub.
4 0.0±0.0 0.0±0.0 0.0±0.0 1.2±0.2*°
7 0.0±0.0 0.0±0.0 0.0±0.0 2.7±0.2*°‡
11 0.0±0.0 0.0±0.0 0.0±0.0 7.5±1.6*°‡†
30 0.0±0.0 1.4±0.2*‡†• 1.6±0.3*‡†• 7.4±2.9*°‡†
Mitosis
4 0.0±0.0 0.0±0.0 0.0±0.0 2.2±0.8*°
7 0.0±0.0 0.0±0.0 0.0±0.0 3.7±0.2*°‡
11 0.0±0.0) 1.7±0.2*‡† 1.5±0.3*‡† 4.5±0.3*°‡†
30 0.0±0.0 1.7±0.2*‡† 1.5±0.2*‡† 4.9±0.9*°‡†
Solid Sheets
4 0.0±0.0 0.0±0.0 0.0±0.0 2.8±0.8*°
7 0.0±0.0 0.0±0.0 0.0±0.0 4.8±0.6*°‡
11 0.0±0.0 0.0±0.0 0.0±0.0 5.7±0.5*°‡
30 0.0±0.0 1.3±0.2*‡†• 1.4±0.4*‡†• 6.9±2.8*°‡
Int. Fibrosis
4 0.0±0.0 0.0±0.0 0.0±0.0 0.0±0.0
7 0.0±0.0) 23.7±0.91* 23.1±1.4* 4.6±0.3*°‡
11 0.0±0.0 34.2±1.3*‡† 32.8±2.3*‡† 11.9±1.8*‡°†
30 0.0±0.0) 47.6±2.6*‡†• 43.7±2.7*‡†• 17.8±1.7*°‡†•
Atrophic Tub.
4 0.0±0.0 13.3±2.3* 12.5±1.4* 6.5±0.3*°
7 0.0±0.0 12.7±1.2* 12.5±1.3* 4.7±0.4*°‡
11 0.0±0.0 12.4±0.8* 12.3±0.6* 3.8±1.8*°‡
30 0.0±0.0 4.4±0.2*‡†• 4.6±0.2*‡†• 2.8±0.6*°‡†

Significant difference compared to corresponding * control, ° cisplatin groups

Significant difference compared to intragroup day4, day7, day11 Kruskal-Wallis test at P≤0.05