Table 3.
Statistical testing of model scenarios: here ‘model’ refers to the NC targeting model and ‘null’ refers to model representing the null hypothesis (see §2); the comparison (r2) is between modeland experiment; ‘all’ refers to comparison across all organs and ‘lung’ refers to comparison for lung alone. (* indicates the activated form of cells.)
| hypothesis | flat substrate | membrane | membrane + other cells | membrane + other cells* |
|---|---|---|---|---|
| r2: all/model | 0.76 ± 0.003 | 0.77 ± 0.003 | 0.69 ± 0.005 | 0.64 ± 0.001 |
| r2: all/null | 0.59 ± 0.003 | 0.47 ± 0.001 | 0.37 ± 0.005 | 0.374 ± 0.003 |
| p-value all | 6×10−13 | 2×10−14 | 1×10−15 | 2×10−12 |
| (model versus null) | ||||
| r2: lung/model | 0.57 ± 0.009 | 0.88 ± 0.002 | 0.88 ± 0.002 | 0.88 ± 0.002 |
| r2: lung/null | 0.94 ± 0.003 | 0.61 ± 0.002 | 0.61 ± 0.002 | 0.61 ± 0.002 |
| p-value lung | 4×10−07 | 5×10−7 | 5×10−7 | 5×10−7 |
| (model versus null) |