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A translocation intermediate suggestive of cohesin sliding. (a) A model depicting a cohesin sliding intermediate. (b) Time course analysis of cohesin translocation at the GAL2 locus in cells arrested in G2/M and shifted to 16°C for 1 h before galactose addition. (c) Cohesin behaviour at the synthetic GAL2 promoter-UTP20 locus, following galactose induction as in (b).
