TABLE 2.
Baseline Patient Characteristics and Treatments
| Emory University Hospital | University of Nebraska Medical Center | Texas Health Presbyterian Dallas Hospital | |
|---|---|---|---|
| Age (yr) | 43 | 44 | 42 |
| Sex | Male | Male | Male |
| Day of illness at time of diagnosis | 2 | 8 | 7 |
| Ebola virus Ct value | |||
| At the time of diagnosis/day of illness | 24/day 2 | 21.2/day 14 | 23/day 3 |
| Peak/day of illness | 20/day 7 | 19.5/Unknown | 17/day 6 |
| Organ involvement | |||
| Liver | Yes | Yes | Yes |
| Gastrointestinal symptoms | Yes | Yes | Yes |
| Muscle (myositis) | Likely (aspartate aminotransferase) | Yes (CPK > 4,100) | Likely (CPK 1,917) |
| Skin | Yes | No | No |
| CNS | Yes | Yes | No |
| Renal | Yes | Yes | Yes |
| Pulmonary | Yes | Yes | Yes |
| Ventilator | |||
| Start | Day 9 | Day 13 | Day 11 |
| Length | 17 d | 3 d | 5 d |
| Mode | AC-VC > AC-PC | AC-VC | AC-PC |
| Tidal volume (mL/kg, VC) | 5.5–6.6 | 6.8–8.1 | Not available |
| Lactic acid (mmol/L) | ≤ 2.8 | ≤ 10.4 | ≤ 6.57 |
| Experimental treatment(s) received | TKM-100802 and convalescent plasma | Zmapp, convalescent blood, and plasma | Brincidofovir |
CPK = creatinine phosphokinase, AC-VC = assist control - volume control, AC-PC = assist control or pressure control.