Figure 2. Analysis of cardiac morphology .

Representative formalin fixed hearts from WT, TnI^PKA−, MyBPC^PKA− and DBL^PKA− mice. After formalin fixation, representative hearts were imaged (A) (scale bar = 1 mm) before being sectioned at the mid LV and imaged again (B) (scale bar = 1 mm). C, cross‐sections of the mid LV were stained with Masson's trichrome and imaged at 100× magnification (scale bar = 50 μm). D, summary data showing heart weight normalized to body weight for each line. Values are expressed as the mean ± SEM from four or five mice per line. *Significantly different from WT (P < 0.05). E, quantification of fibrosis from Masson's trichrome cardiac sections in (C). Values are expressed as the mean ± SEM and cardiac sections were analysed from four or five mice per line.