Figure 4. BF-lHb does not initiate attack but modulates aggression severity.
(a) Schematic of optogenetic (a) viral infection strategy and (b) aggression procedure. NON (c) attack latency, (d) attack duration, (e) social exploration and (f) non-social exploration behaviors in pretest and test sessions (non-significant, n = 7–8/group). AGG (g) attack latency (F2,42 = 6.01, two-way ANOVA P <0.001, *P<0.05, n = 7–9/group), (h) attack duration (F2,42 = 5.666, two-way ANOVA P <0.001, *P<0.05, n = 7–9/group), (i) social exploration and (j) non-social exploration behaviors in pretest and test sessions. NON, non-aggressor; AGG, aggressor; lHb, lateral habenula; BF, basal forebrain.
