Table 2. The correlation of serum p75NTR-ECD with neuropsychological evaluation score.
|
Unadjusted |
Adjusteda |
|||||
|---|---|---|---|---|---|---|
| r-value | 95% CI | P-value | r-value | 95% CI | P-value | |
| MMSE | ||||||
| Overall | −0.472 | −0.558–−0.377 | <0.001 | −0.482 | −0.592–−0.364 | <0.001 |
| AD | −0.363 | −0.492–−0.219 | <0.001 | −0.374 | −0.500–−0.213 | <0.001 |
| CDR | ||||||
| Overall | 0.457 | 0.360–0.545 | <0.001 | 0.460 | 0.341–−0.577 | <0.001 |
| AD | 0.305 | 0.157–0.441 | <0.001 | 0.304 | 0.142–0.453 | <0.001 |
| ADL | ||||||
| Overall | 0.443 | 0.345–0.532 | <0.001 | 0.438 | 0.304–0.551 | <0.001 |
| AD | 0.325 | 0.177–0.459 | <0.001 | 0.320 | 0.160–0.453 | <0.001 |
Abbreviations: AD, Alzheimer's disease; ADL, activities of daily living; CDR, clinical dementia rating; CI, confidence interval; MMSE, mini-mental state examination; p75NTR-ECD, ectodomain of p75 neurotrophin receptor.
Adjusted for age, sex, education, hyperlipidaemia, hypertension and diabetes.